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Table 5 Determinants of global longitudinal early diastolic strain rate

From: Characterization of subclinical diastolic dysfunction by cardiac magnetic resonance feature-tracking in adult survivors of non-Hodgkin lymphoma treated with anthracyclines

Independent variables Dependent variable (GLSR-E)
Univariate analysis Multiple Analysis (r2 0.44, p < 0.001)
B Coef 95% CI p B Coef 95% CI p
Cumulative dose − 0.03 (− 0.06;− 0.01) 0.009 – – –
Time after therapy 0.07 (− 0.05;0.19) 0.245 – – –
Age (years) − 0.28 (− 0.70;0.13) 0.173 − 0.43 (− 0.76;0.10) 0.012
Gender (female) 7.45 (− 4.70;19.60) 0.212 – – –
Smoking (Yes) − 0.56 (− 36.63;35.51) 0.975 – – –
Hypertension (no) 9.12 (− 4.24;22.48) 0.174 – – –
Diabetes (no) − 13.74 (− 34.65;7.16) 0.190 – – –
Dyslipidemia (no) 12.87 (− 22.91;48.65) 0.469 – – –
Prior radiotherapy (no) − 2.80 (− 28.67;23.07) 0.827 – – –
LVEF 1.25 (0.47;2.02) 0.002 – – –
LVMi − 0.25 (− 0.85;0.33) 0.384 – – –
LGE (no) − 2.80 (− 28.67;23.07) 0.827 – – –
Native T1 − 0.05 (− 0.23;0.13) 0.559 – – –
ECV 0.33 (− 1.64;2.31) 0.730 – – –
T2 − 0.27 (− 3.41;2.87) 0.861 – – –
GLS − 3.65 (− 5.53;− 1.77)  < 0.001 − 4.09 (− 5.86;− 2.33)  < 0.001
  1. LVEF left ventricular ejection fraction, LVMi left ventricular mass index, LGE late gadolinium enhancement, ECV extracellular volume fraction, GLS global longitudinal strain
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BMC Cardiovascular Disorders

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